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This effect, mediated by inactivation of the phosphoinositide 3-kinase activation (PI3K/AKT) and extracellular-signal-regulated kinase (ERK) signaling pathways, offers an insight into the complex mechanisms of miscarriage and preeclampsia during Se deficiency

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Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: A potential therapeutic approach for alzheimer's disease